FINHUB Insights

Vertex Pharmaceuticals insider activity

VRTX · VRTX income statements · EDGAR

What the executives and directors of Vertex Pharmaceuticals actually did with their own shares, decoded from their SEC Form 4 filings. Each figure says the stretch of time it covers.

−$158M net open-market flow, 12 m
0 open-market buys, 12 m
100% of sale value on 10b5-1 plans, 12 m
411 days since an insider bought, whole record

The tape: three years of insider trades

Open-market buy Discretionary sale Planned sale (10b5-1) Reported-price path Routine

Every marker sits at the price reported on the Form 4. The line is the monthly median of all prices insiders reported, so the chart needs no market feed; the grey strip is the routine flow (grants, vestings, tax withholding and gifts) that a headline gets wrong by counting it as selling.

The 149 routine events on the chart, as a list
Date Insider Shares
Sep 8, 2026 van Grunsven Jasper 8,682
Aug 28, 2026 Ambrose Kristen 5,000
Aug 27, 2026 SACHS BRUCE I 6,000
Jul 21, 2026 Sachdev Amit 8,251
Jul 21, 2026 Tatsis Ourania 8,251
May 1, 2026 Garber Alan M 472
May 1, 2026 Bhatia Sangeeta N. 943
May 1, 2026 MCKENZIE DIANA 943
May 1, 2026 Schneider Jennifer 472
May 1, 2026 Thornberry Nancy 472
Feb 24, 2026 WAGNER CHARLES F JR 1,744
Feb 24, 2026 LEIDEN JEFFREY M 3,547
Feb 24, 2026 Sachdev Amit 1,518
Feb 24, 2026 Kewalramani Reshma 4,981
Feb 24, 2026 Biller Jonathan 1,144
Feb 24, 2026 Tatsis Ourania 1,627
Feb 24, 2026 Bozic Carmen 1,453
Feb 24, 2026 Ambrose Kristen 546
Feb 24, 2026 Atkinson Edward Morrow III 1,627
Feb 24, 2026 McKechnie Duncan 873
Feb 24, 2026 Bunnage Mark E. 582
Feb 19, 2026 Sachdev Amit 56K
Feb 18, 2026 LEIDEN JEFFREY M 11K
Feb 17, 2026 WAGNER CHARLES F JR 9,659
Feb 17, 2026 Kewalramani Reshma 23K
Feb 17, 2026 Biller Jonathan 5,640
Feb 17, 2026 Tatsis Ourania 8,083
Feb 17, 2026 Bozic Carmen 7,287
Feb 17, 2026 Ambrose Kristen 2,407
Feb 17, 2026 Atkinson Edward Morrow III 6,492
Feb 17, 2026 McKechnie Duncan 6,110
Feb 17, 2026 Bunnage Mark E. 3,694
Feb 13, 2026 WAGNER CHARLES F JR 7,610
Feb 13, 2026 Sachdev Amit 5,605
Feb 13, 2026 Kewalramani Reshma 21K
Feb 13, 2026 Biller Jonathan 4,623
Feb 13, 2026 Tatsis Ourania 5,944
Feb 13, 2026 Bozic Carmen 5,949
Feb 13, 2026 Ambrose Kristen 1,985
Feb 13, 2026 Atkinson Edward Morrow III 2,775
Feb 13, 2026 McKechnie Duncan 3,410
Feb 13, 2026 Bunnage Mark E. 3,410
Jan 22, 2026 WAGNER CHARLES F JR 14K
Jan 22, 2026 LEIDEN JEFFREY M 9,012
Jan 22, 2026 Sachdev Amit 12K
Jan 22, 2026 ALTSHULER DAVID 11K
Jan 22, 2026 Kewalramani Reshma 39K
Jan 22, 2026 Biller Jonathan 9,068
Jan 22, 2026 Tatsis Ourania 12K
Jan 22, 2026 Bozic Carmen 11K
Jan 22, 2026 Ambrose Kristen 4,250
Jan 22, 2026 Atkinson Edward Morrow III 7,817
Jan 22, 2026 McKechnie Duncan 6,800
Jan 6, 2026 WAGNER CHARLES F JR 9,532
Dec 4, 2025 LEIDEN JEFFREY M 64K
Nov 19, 2025 CARNEY LLOYD 800
Nov 14, 2025 LEIDEN JEFFREY M 73K
Oct 1, 2025 Biller Jonathan 1,259
Jul 1, 2025 Arbuckle Stuart A 37K
May 13, 2025 Arbuckle Stuart A 38K

The 60 most recent of 149.

Where the shares went, last 12 months

Every Form 4 movement decomposed: what flowed in (grants, vested equity, purchases) and what flowed out (tax withholding, plan sales, discretionary sales, gifts). Counted in shares, because grants carry no price.

The chart, in numbers
Flow Shares
From holdings 29K
Granted 236K
Vested / exercised 195K
Withheld for tax 110K
Planned sales (10b5-1) 343K
Gifts 6,800

Skin in the game

Directly held shares as reported after each trade, indexed to 100 at the start of the window, up to five years back. Direct holdings only: trust and family-entity positions are per-entity in the filings and do not sum honestly, so this chart refuses to guess. The steps are the trades.

The chart, in numbers
Insider Start of the window Latest reported Indexed, start = 100
Kewalramani Reshma 142K 98K 69.4
Sachdev Amit 32K 67K 208.3
Arbuckle Stuart A 41K 63K 154.2
Tatsis Ourania 59K 54K 90.4
WAGNER CHARLES F JR 60K 47K 77.9

Who holds what

the 14 largest holdings of 24
Insider Role Shares held Buys 12 m Sales 12 m 12 m Last trade
Kewalramani Reshma CEO & President Last trade Feb 27, 2026 CEO 138K $20M net selling over the year: 0 months buying, 1 month selling Feb 27, 2026
Sachdev Amit EVP Chief Patient & Ext Af Off Last trade Feb 25, 2026 Officer 67K $28M net selling over the year: 0 months buying, 1 month selling Feb 25, 2026
Arbuckle Stuart A EVP, COO Last trade May 15, 2024 COO 63K May 15, 2024
Tatsis Ourania EVP, Chief Reg. & Quality Off. Last trade Jul 2, 2026 Officer 54K $6.5M net selling over the year: 0 months buying, 4 months selling Jul 2, 2026
WAGNER CHARLES F JR EVP, CO & FO Last trade Jan 6, 2026 Officer 47K $11M net selling over the year: 0 months buying, 2 months selling Jan 6, 2026
SACHS BRUCE I Last trade Aug 6, 2025 Director 39K Aug 6, 2025
LEIDEN JEFFREY M Executive Chairman Last trade Dec 3, 2025 Officer 35K $61M net selling over the year: 0 months buying, 2 months selling Dec 3, 2025
ALTSHULER DAVID EVP, Chief Scientific Officer Last trade May 15, 2025 Officer 31K May 15, 2025
Liu Joy EVP and Chief Legal Officer Last trade Jul 1, 2026 Officer 19K $2.1M net selling over the year: 0 months buying, 5 months selling Jul 1, 2026
Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Last trade Feb 25, 2026 Officer 18K $3.6M net selling over the year: 0 months buying, 2 months selling Feb 25, 2026
Bozic Carmen EVP and CMO Last trade Jun 26, 2026 Officer 15K $11M net selling over the year: 0 months buying, 4 months selling Jun 26, 2026
Biller Jonathan EVP and Chief Legal Officer Last trade Feb 25, 2026 Officer 14K $4.1M net selling over the year: 0 months buying, 3 months selling Feb 25, 2026
Ambrose Kristen SVP & Chief Accounting Officer Last trade Feb 26, 2026 Officer 12K $2.0M net selling over the year: 0 months buying, 1 month selling Feb 26, 2026
McKechnie Duncan EVP, Chief Commercial Officer Last trade Jul 2, 2026 Officer 11K $5.7M net selling over the year: 0 months buying, 3 months selling Jul 2, 2026

Open-market trade log

the 60 most recent of 3,807
Date Insider Type Shares Price Value Since trade Filed
Jul 2, 2026 Tatsis Ourania (Officer) 1,500 shares $524.99 −1.1% since trade filed Jul 7, 2026 Planned sale (10b5-1) 1,500 $524.99 $787K −1.1% Jul 7, 2026
Jul 2, 2026 McKechnie Duncan (Officer) 1,541 shares $519.00 +0.0% since trade filed Jul 7, 2026 Planned sale (10b5-1) 1,541 $519.00 $800K +0.0% Jul 7, 2026
Jul 1, 2026 Liu Joy (Officer) 828 shares $502.71 +3.2% since trade filed Jul 6, 2026 Planned sale (10b5-1) 828 $502.71 $416K +3.2% Jul 6, 2026
Jun 26, 2026 Bozic Carmen (Officer) 596 shares $482.50 +7.6% since trade filed Jun 30, 2026 Planned sale (10b5-1) 596 $482.50 $288K +7.6% Jun 30, 2026
Jun 18, 2026 Bozic Carmen (Officer) 1,020 shares $462.17 +12.3% since trade filed Jun 23, 2026 Planned sale (10b5-1) 1,020 $462.17 $471K +12.3% Jun 23, 2026
Jun 15, 2026 Bozic Carmen (Officer) 4,062 shares $450.00 +15.3% since trade filed Jun 17, 2026 Planned sale (10b5-1) 4,062 $450.00 $1.8M +15.3% Jun 17, 2026
Jun 5, 2026 Bozic Carmen (Officer) 1,745 shares $450.00 +15.3% since trade filed Jun 9, 2026 Planned sale (10b5-1) 1,745 $450.00 $785K +15.3% Jun 9, 2026
Jun 1, 2026 Liu Joy (Officer) 828 shares $439.91 +18.0% since trade filed Jun 3, 2026 Planned sale (10b5-1) 828 $439.91 $364K +18.0% Jun 3, 2026
May 29, 2026 Bozic Carmen (Officer) 1,974 shares $450.00 +15.3% since trade filed Jun 2, 2026 Planned sale (10b5-1) 1,974 $450.00 $888K +15.3% Jun 2, 2026
May 15, 2026 Bozic Carmen (Officer) 1,354 shares $453.45 +14.5% since trade filed May 19, 2026 Planned sale (10b5-1) 1,354 $453.45 $614K +14.5% May 19, 2026
May 15, 2026 Bunnage Mark E. (Officer) 33 shares $453.45 +14.5% since trade filed May 19, 2026 Planned sale (10b5-1) 33 $453.45 $15K +14.5% May 19, 2026
May 12, 2026 Bozic Carmen (Officer) 6,988 shares $450.00 +15.3% since trade filed May 14, 2026 Planned sale (10b5-1) 6,988 $450.00 $3.1M +15.3% May 14, 2026
May 4, 2026 Bhatia Sangeeta N. (Director) 318 shares $423.73 +22.5% since trade filed May 5, 2026 Planned sale (10b5-1) 318 $423.73 $135K +22.5% May 5, 2026
May 1, 2026 Liu Joy (Officer) 1,104 shares $425.02 +22.1% since trade filed May 5, 2026 Planned sale (10b5-1) 1,104 $425.02 $469K +22.1% May 5, 2026
Apr 1, 2026 Liu Joy (Officer) 978 shares $449.17 +15.6% since trade filed Apr 3, 2026 Planned sale (10b5-1) 978 $449.17 $439K +15.6% Apr 3, 2026
Mar 27, 2026 Bozic Carmen (Officer) 2,329 shares $450.95 +15.1% since trade filed Mar 31, 2026 Planned sale (10b5-1) 2,329 $450.95 $1.1M +15.1% Mar 31, 2026
Mar 13, 2026 Bozic Carmen (Officer) 2,329 shares $481.79 +7.7% since trade filed Mar 17, 2026 Planned sale (10b5-1) 2,329 $481.79 $1.1M +7.7% Mar 17, 2026
Mar 11, 2026 McKechnie Duncan (Officer) 2,633 shares $498.42 +4.1% since trade filed Mar 13, 2026 Planned sale (10b5-1) 2,633 $498.42 $1.3M +4.1% Mar 13, 2026
Mar 4, 2026 McKechnie Duncan (Officer) 2,437 shares $475.30 +9.2% since trade filed Mar 6, 2026 Planned sale (10b5-1) 2,437 $475.30 $1.2M +9.2% Mar 6, 2026
Mar 2, 2026 Liu Joy (Officer) 892 shares $495.96 +4.7% since trade filed Mar 4, 2026 Planned sale (10b5-1) 892 $495.96 $442K +4.7% Mar 4, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 120 shares $481.50 +7.8% since trade filed Mar 3, 2026 Planned sale (10b5-1) 120 $481.50 $58K +7.8% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 240 shares $482.84 +7.5% since trade filed Mar 3, 2026 Planned sale (10b5-1) 240 $482.84 $116K +7.5% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 400 shares $479.75 +8.2% since trade filed Mar 3, 2026 Planned sale (10b5-1) 400 $479.75 $192K +8.2% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 460 shares $489.32 +6.1% since trade filed Mar 3, 2026 Planned sale (10b5-1) 460 $489.32 $225K +6.1% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 949 shares $491.30 +5.6% since trade filed Mar 3, 2026 Planned sale (10b5-1) 949 $491.30 $466K +5.6% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 1,725 shares $496.95 +4.4% since trade filed Mar 3, 2026 Planned sale (10b5-1) 1,725 $496.95 $857K +4.4% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 2,510 shares $487.13 +6.5% since trade filed Mar 3, 2026 Planned sale (10b5-1) 2,510 $487.13 $1.2M +6.5% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 2,520 shares $493.29 +5.2% since trade filed Mar 3, 2026 Planned sale (10b5-1) 2,520 $493.29 $1.2M +5.2% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 2,725 shares $490.54 +5.8% since trade filed Mar 3, 2026 Planned sale (10b5-1) 2,725 $490.54 $1.3M +5.8% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 3,278 shares $488.27 +6.3% since trade filed Mar 3, 2026 Planned sale (10b5-1) 3,278 $488.27 $1.6M +6.3% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 3,498 shares $494.33 +5.0% since trade filed Mar 3, 2026 Planned sale (10b5-1) 3,498 $494.33 $1.7M +5.0% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 5,995 shares $496.16 +4.6% since trade filed Mar 3, 2026 Planned sale (10b5-1) 5,995 $496.16 $3.0M +4.6% Mar 3, 2026
Feb 27, 2026 Kewalramani Reshma (CEO) 16K shares $495.38 +4.8% since trade filed Mar 3, 2026 Planned sale (10b5-1) 16K $495.38 $7.7M +4.8% Mar 3, 2026
Feb 27, 2026 Bozic Carmen (Officer) 2,329 shares $480.31 +8.1% since trade filed Mar 3, 2026 Planned sale (10b5-1) 2,329 $480.31 $1.1M +8.1% Mar 3, 2026
Feb 26, 2026 Ambrose Kristen (Officer) 357 shares $483.36 +7.4% since trade filed Mar 2, 2026 Planned sale (10b5-1) 357 $483.36 $173K +7.4% Mar 2, 2026
Feb 25, 2026 Sachdev Amit (Officer) 1,846 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 1,846 $486.35 $898K +6.7% Feb 26, 2026
Feb 25, 2026 Biller Jonathan (Officer) 945 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 945 $486.35 $460K +6.7% Feb 26, 2026
Feb 25, 2026 Tatsis Ourania (Officer) 260 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 260 $486.35 $126K +6.7% Feb 26, 2026
Feb 25, 2026 Ambrose Kristen (Officer) 223 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 223 $486.35 $108K +6.7% Feb 26, 2026
Feb 25, 2026 Atkinson Edward Morrow III (Officer) 668 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 668 $486.35 $325K +6.7% Feb 26, 2026
Feb 25, 2026 McKechnie Duncan (Officer) 2,410 shares $489.00 +6.1% since trade filed Feb 26, 2026 Planned sale (10b5-1) 2,410 $489.00 $1.2M +6.1% Feb 26, 2026
Feb 25, 2026 McKechnie Duncan (Officer) 2,500 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 2,500 $486.35 $1.2M +6.7% Feb 26, 2026
Feb 25, 2026 Bunnage Mark E. (Officer) 620 shares $486.35 +6.7% since trade filed Feb 26, 2026 Planned sale (10b5-1) 620 $486.35 $302K +6.7% Feb 26, 2026
Feb 19, 2026 Sachdev Amit (Officer) 920 shares $463.91 +11.9% since trade filed Feb 23, 2026 Planned sale (10b5-1) 920 $463.91 $427K +11.9% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 1,848 shares $465.80 +11.4% since trade filed Feb 23, 2026 Planned sale (10b5-1) 1,848 $465.80 $861K +11.4% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 2,730 shares $465.05 +11.6% since trade filed Feb 23, 2026 Planned sale (10b5-1) 2,730 $465.05 $1.3M +11.6% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 4,237 shares $471.43 +10.1% since trade filed Feb 23, 2026 Planned sale (10b5-1) 4,237 $471.43 $2.0M +10.1% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 7,241 shares $469.61 +10.5% since trade filed Feb 23, 2026 Planned sale (10b5-1) 7,241 $469.61 $3.4M +10.5% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 10K shares $467.75 +11.0% since trade filed Feb 23, 2026 Planned sale (10b5-1) 10K $467.75 $4.8M +11.0% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 12K shares $470.54 +10.3% since trade filed Feb 23, 2026 Planned sale (10b5-1) 12K $470.54 $5.5M +10.3% Feb 23, 2026
Feb 19, 2026 Sachdev Amit (Officer) 20K shares $468.57 +10.8% since trade filed Feb 23, 2026 Planned sale (10b5-1) 20K $468.57 $9.2M +10.8% Feb 23, 2026
Feb 18, 2026 Biller Jonathan (Officer) 1,244 shares $473.68 +9.6% since trade filed Feb 19, 2026 Planned sale (10b5-1) 1,244 $473.68 $589K +9.6% Feb 19, 2026
Feb 18, 2026 Tatsis Ourania (Officer) 368 shares $473.68 +9.6% since trade filed Feb 19, 2026 Planned sale (10b5-1) 368 $473.68 $174K +9.6% Feb 19, 2026
Feb 18, 2026 Ambrose Kristen (Officer) 638 shares $473.68 +9.6% since trade filed Feb 19, 2026 Planned sale (10b5-1) 638 $473.68 $302K +9.6% Feb 19, 2026
Feb 18, 2026 Atkinson Edward Morrow III (Officer) 817 shares $473.68 +9.6% since trade filed Feb 19, 2026 Planned sale (10b5-1) 817 $473.68 $387K +9.6% Feb 19, 2026
Feb 18, 2026 Bunnage Mark E. (Officer) 1,182 shares $473.68 +9.6% since trade filed Feb 19, 2026 Planned sale (10b5-1) 1,182 $473.68 $560K +9.6% Feb 19, 2026
Feb 17, 2026 Biller Jonathan (Officer) 2,476 shares $489.46 +6.0% since trade filed Feb 19, 2026 Planned sale (10b5-1) 2,476 $489.46 $1.2M +6.0% Feb 19, 2026
Feb 17, 2026 Tatsis Ourania (Officer) 609 shares $489.46 +6.0% since trade filed Feb 19, 2026 Planned sale (10b5-1) 609 $489.46 $298K +6.0% Feb 19, 2026
Feb 17, 2026 Ambrose Kristen (Officer) 1,557 shares $489.46 +6.0% since trade filed Feb 19, 2026 Planned sale (10b5-1) 1,557 $489.46 $762K +6.0% Feb 19, 2026
Feb 17, 2026 Atkinson Edward Morrow III (Officer) 2,031 shares $489.46 +6.0% since trade filed Feb 19, 2026 Planned sale (10b5-1) 2,031 $489.46 $994K +6.0% Feb 19, 2026

“Since trade” compares with the latest insider-implied price, not a market quote: these pages are built from filings alone. A role here is the one on that day's Form 4, so somebody promoted since appears under both titles.

Filing hygiene

321 Forms 4, 3 years
0 filed late
0 amendments
2.1 avg. days to file

How to read this

A Form 4 transaction code decides everything. P is an open-market purchase and S an open-market sale; those two are the only codes where an insider chose to trade. A is a grant, M an option exercise or vesting, F shares withheld to cover tax, G a gift. Most “insiders dumped billions” headlines are code F and M mechanics.

Sales flagged 10b5-1 run on a plan the insider adopted in advance; since 2023 every Form 4 carries that flag. Buys have historically predicted returns, sales mostly have not, and this page states filings, not advice.

Every number on this page comes from Forms 3, 4 and 5 filed with the SEC. The insider export runs on its own schedule, so it can be a few days behind the rest of the site; the date below says how far it goes. Browse the source filings on SEC EDGAR. Data through Sep 18, 2026