What the executives and directors of Vertex Pharmaceuticals actually did with their own shares, decoded from three years of SEC Form 4 filings.
The tape: three years of insider trades
Every marker sits at the exact price reported on the Form 4. The line is the monthly median of all prices insiders reported, so the chart needs no market feed; the gray strip is routine flow (vestings, tax withholding, gifts) that headlines love to miscount as selling.
Where the shares went, last 12 months
Every Form 4 movement decomposed: what flowed in (grants, vested equity, purchases) and what flowed out (tax withholding, plan sales, discretionary sales, gifts). Counted in shares, because grants carry no price.
Skin in the game
Directly held shares as reported after each trade, indexed to 100 five years back. Direct holdings only: trust and family-entity positions are per-entity in the filings and do not sum honestly, so this chart refuses to guess. The steps are the trades.
Who holds what
| Insider | Role | Shares held | Buys 12 m | Sales 12 m |
|---|---|---|---|---|
| Kewalramani Reshma CEO & President | CEO | 137.9K | $3.9M | $19.7M |
| Sachdev Amit EVP Chief Patient & Ext Af Off | Officer | 66.5K | — | $28.4M |
| Arbuckle Stuart A EVP, COO | COO | 63.4K | — | — |
| Tatsis Ourania EVP, Chief Reg. & Quality Off. | Officer | 53.6K | — | $6.5M |
| WAGNER CHARLES F JR EVP, CO & FO | Officer | 47K | — | $10.8M |
| SACHS BRUCE I | Director | 41.6K | $1.9M | — |
| LEIDEN JEFFREY M Executive Chairman | Officer | 34.8K | — | $60.9M |
| ALTSHULER DAVID EVP, Chief Scientific Officer | Officer | 31.1K | — | — |
| Liu Joy EVP and Chief Legal Officer | Officer | 19.1K | — | $2.1M |
| Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. | Officer | 18.4K | — | $3.6M |
| Kearney Terrence C | Director | 16.5K | — | — |
| Bozic Carmen EVP and CMO | Officer | 15.3K | — | $11.3M |
| Biller Jonathan EVP and Chief Legal Officer | Officer | 13.7K | — | $4.1M |
| McKechnie Duncan EVP, Chief Commercial Officer | Officer | 11K | — | $5.7M |
Open-market trade log
| Date | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-07-02 | Tatsis Ourania (Officer) | Planned sale (10b5-1) | 1,500 | $524.99 | $787K |
| 2026-07-02 | McKechnie Duncan (Officer) | Planned sale (10b5-1) | 1,541 | $519.00 | $800K |
| 2026-07-01 | Liu Joy (Officer) | Planned sale (10b5-1) | 828 | $502.71 | $416K |
| 2026-06-26 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 596 | $482.50 | $288K |
| 2026-06-18 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 1,020 | $462.17 | $471K |
| 2026-06-15 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 4,062 | $450.00 | $1.8M |
| 2026-06-05 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 1,745 | $450.00 | $785K |
| 2026-06-01 | Liu Joy (Officer) | Planned sale (10b5-1) | 828 | $439.91 | $364K |
| 2026-05-29 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 1,974 | $450.00 | $888K |
| 2026-05-15 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 1,354 | $453.45 | $614K |
| 2026-05-15 | Bunnage Mark E. (Officer) | Planned sale (10b5-1) | 33 | $453.45 | $15K |
| 2026-05-12 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 6,988 | $450.00 | $3.1M |
| 2026-05-04 | Bhatia Sangeeta N. (Director) | Planned sale (10b5-1) | 318 | $423.73 | $135K |
| 2026-05-01 | Liu Joy (Officer) | Planned sale (10b5-1) | 1,104 | $425.02 | $469K |
| 2026-04-01 | Liu Joy (Officer) | Planned sale (10b5-1) | 978 | $449.17 | $439K |
| 2026-03-27 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 2,329 | $450.95 | $1.1M |
| 2026-03-13 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 2,329 | $481.79 | $1.1M |
| 2026-03-11 | McKechnie Duncan (Officer) | Planned sale (10b5-1) | 2,633 | $498.42 | $1.3M |
| 2026-03-04 | McKechnie Duncan (Officer) | Planned sale (10b5-1) | 2,437 | $475.30 | $1.2M |
| 2026-03-02 | Liu Joy (Officer) | Planned sale (10b5-1) | 892 | $495.96 | $442K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 120 | $481.50 | $58K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 240 | $482.84 | $116K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 400 | $479.75 | $192K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 460 | $489.32 | $225K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 949 | $491.30 | $466K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 1,725 | $496.95 | $857K |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 2,510 | $487.13 | $1.2M |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 2,520 | $493.29 | $1.2M |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 2,725 | $490.54 | $1.3M |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 3,278 | $488.27 | $1.6M |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 3,498 | $494.33 | $1.7M |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 5,995 | $496.16 | $3M |
| 2026-02-27 | Kewalramani Reshma (CEO) | Planned sale (10b5-1) | 15.6K | $495.38 | $7.7M |
| 2026-02-27 | Bozic Carmen (Officer) | Planned sale (10b5-1) | 2,329 | $480.31 | $1.1M |
| 2026-02-26 | Ambrose Kristen (Officer) | Planned sale (10b5-1) | 357 | $483.36 | $173K |
| 2026-02-25 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 1,846 | $486.35 | $898K |
| 2026-02-25 | Biller Jonathan (Officer) | Planned sale (10b5-1) | 945 | $486.35 | $460K |
| 2026-02-25 | Tatsis Ourania (Officer) | Planned sale (10b5-1) | 260 | $486.35 | $126K |
| 2026-02-25 | Ambrose Kristen (Officer) | Planned sale (10b5-1) | 223 | $486.35 | $108K |
| 2026-02-25 | Atkinson Edward Morrow III (Officer) | Planned sale (10b5-1) | 668 | $486.35 | $325K |
| 2026-02-25 | McKechnie Duncan (Officer) | Planned sale (10b5-1) | 2,410 | $489.00 | $1.2M |
| 2026-02-25 | McKechnie Duncan (Officer) | Planned sale (10b5-1) | 2,500 | $486.35 | $1.2M |
| 2026-02-25 | Bunnage Mark E. (Officer) | Planned sale (10b5-1) | 620 | $486.35 | $302K |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 920 | $463.91 | $427K |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 1,848 | $465.80 | $861K |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 2,730 | $465.05 | $1.3M |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 4,237 | $471.43 | $2M |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 7,241 | $469.61 | $3.4M |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 10.3K | $467.75 | $4.8M |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 11.7K | $470.54 | $5.5M |
| 2026-02-19 | Sachdev Amit (Officer) | Planned sale (10b5-1) | 19.7K | $468.57 | $9.2M |
| 2026-02-18 | Biller Jonathan (Officer) | Planned sale (10b5-1) | 1,244 | $473.68 | $589K |
| 2026-02-18 | Tatsis Ourania (Officer) | Planned sale (10b5-1) | 368 | $473.68 | $174K |
| 2026-02-18 | Ambrose Kristen (Officer) | Planned sale (10b5-1) | 638 | $473.68 | $302K |
| 2026-02-18 | Atkinson Edward Morrow III (Officer) | Planned sale (10b5-1) | 817 | $473.68 | $387K |
| 2026-02-18 | Bunnage Mark E. (Officer) | Planned sale (10b5-1) | 1,182 | $473.68 | $560K |
| 2026-02-17 | Biller Jonathan (Officer) | Planned sale (10b5-1) | 2,476 | $489.46 | $1.2M |
| 2026-02-17 | Tatsis Ourania (Officer) | Planned sale (10b5-1) | 609 | $489.46 | $298K |
| 2026-02-17 | Ambrose Kristen (Officer) | Planned sale (10b5-1) | 1,557 | $489.46 | $762K |
| 2026-02-17 | Atkinson Edward Morrow III (Officer) | Planned sale (10b5-1) | 2,031 | $489.46 | $994K |
“Since trade” compares with the latest insider-implied price, not a market quote; this site carries no market data by design.
Filing hygiene
How to read this
A Form 4 transaction code decides everything. P is an open-market purchase and S an open-market sale; those two are the only codes where an insider chose to trade. A is a grant, M an option exercise or vesting, F shares withheld to cover tax, G a gift. Most “insiders dumped billions” headlines are code F and M mechanics.
Sales flagged 10b5-1 run on a plan the insider adopted in advance; since 2023 every Form 4 carries that flag. Buys have historically predicted returns, sales mostly have not, and this page states filings, not advice.